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Can't get 2 computers to boot from a flash drive

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I can't get 2 of my computers to boot from an Acronis boot drive that I made. I checked the boot drive out in a 3rd computer and it works just fine.

The 2 computers are:

a Dell Inspiron 5000 Series (Model  i5570-3064BLU-PUS) and

a Levono IdeaPad S340 (Model  81QF0002US)

Neither computer's BIOS permits me to boot the system from anything but the internal drive. 

Any help would be greatly appreciated.

 

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How do your Dell Inspiron 5000 and Lenovo IdeaPad S340 boot from the BIOS into Windows here?

If possible, run the command 'msinfo32' (without quotes) on each computer then look at what it shows for BIOS mode in the report produced.  This is also how you need to boot from the Acronis rescue media USB stick.

Next, what type of Acronis rescue media are you using here?

The default media for ATI 2017 & earlier versions is Linux based which may require that Secure Boot is disabled on some UEFI BIOS systems.  The alternative rescue media requires that the Windows ADK be installed to provide the necessary Windows PE files which can then work fine with Secure Boot enabled.

From ATI 2018 onwards, the default media is WinPE based on files from the Windows Recovery Environment (WinRE), which again is fine with Secure Boot.

If you are not able to access the temporary Boot device selection menu (F12 for Dell normally) or pin-hole press for Lenovo, then you can try doing this via the Windows 10 Settings > Recovery panel for selecting a temporary USB boot device.

See KB 59877: Acronis True Image: how to distinguish between UEFI and Legacy BIOS boot modes of Acronis Bootable Media

Neither computer's BIOS permits me to boot the system from anything but the internal drive. 

If this is a bios limitation, that may be an issue.  Most motherboards will allow you to tweak settings to allow booting from a third party drive though.  You may need to refer to you bios firmware user documentation though.

Typically, the controlling setting is secure boot and needs to be disabled. The Dell should be able to modify this for sure.  Some Lenovo's are trickier than others.

Check this youtube video as an example:  

On my Asus and a previous Acer, I had to disable secure boot.  Save and exit the bios.  Then go back in and delete the secure boot keys (they can be recreated again later if you ever want to turn it back on).  Then save and exit the bios again.

On the Acer, I also had to enable CSM/legacy mode to boot anything external.  Even though I was only needing/wanting to boot the USB drive in UEFI mode.  It was a requirement of that particular bios though.  Did that, then used my one-time boot menu option (usually F12, but can be F1, F2, esc, del, or something else depending on the system - dell's are usually F12) and made sure I was using the UEFI boot entry for the USB drive.