Overwhelmed..need help with disk data folder structure/backup strategy

Hello everyone, Long story short, I'm a part-time graphic artist/web designer with a boatload of associated files..Adobe Illustrator files, Adobe Photoshop files, Dreamweaver files, Photo files from my Canon Digital, Font files, Music files... I have about a half-dozen new projects a month. I keep things fairly well organized now, but I think my data could be better organized. I Just finished building a new system (so pressed for time it took me over a year to do it bit by bit) that consists of the following:

120 GB SSD drive for the OS
1 TB Western Digital Black Caviar for everything else
1 TB Western Digital External USB Drive for external backups

I'm trying to organize my data for efficiency in both my work flow and for backup. I'd really like to chat privately or in forum with someone who is of similar occupation, preferably a graphic artist, and how you organize your data and also how you have setup your backup plan. I would really like to not store anything on the SSD if possible, because of it's limited space. I'm looking for prioritizing certain data so as not to

I would be happy to offer a small reward via PayPal if someone can get me from bare drive to working from my new PC. Hope that doesn't raise any eyebrows but I'd like to show my appreciation if someone has a working model for me to duplicate and doesn't mind sharing. Like I said, I'm pressed for time and have about 2 hours a night of free time to workout, shower, eat, then work on PC :)

I'm using Acronis True Image Home 2011, PC Backup and Recovery.